![]() ![]() Thus, in the WHO 2021 classification of CNS tumors, RM are defined based on the presence of rhabdoid cells, i.e., “plump cells with an eccentric nuclei, open chromatin, macronucleoli, and prominent eosinophilic paranuclear inclusions, appearing either as discernible whorled fibrils or compact and waxy spheres”, and RM are classified as WHO grade 3 tumor. Among all meningiomas, rhabdoid meningiomas (RM) are a rare tumor subtype which usually present with unique histopathologic characteristics. Thus, most meningiomas show World Health Organization (WHO) benign grade 1 histopathologic features, while WHO grade 2 and 3 meningiomas are less frequently observed. Meningiomas are the most common subtype of central nervous system (CNS) tumors which display heterogeneous histopathologic and genetic/molecular features that are associated with a usually benign clinical outcome. ![]()
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